very saddend by the news my heart goes out to those effected. I am looking forward to my pup and here are the parents just wondering if anyone can chime in on the sire and Dam thank you
sIRE: Ch. Tenshou Go Awahakuga (Kuma) or Akashima's Kochi Ken Kaiuri
DAM: Daiyuume Go Iyo Tsukasasou (Sachi) or Ch. Akashima's Kochi-Ken Harayuki (Yuki)
@Hinata23 - Last I know he is still being used, so if this is genetic there is a chance he's a carrier. But at the same time, since there is little known about this illness we don't yet have a way to narrow down the cause and genetics of it.
@Calia Well... someone should contact the owner and have him stop breeding Kimi. It's rare, but two litter mates got it. It's wasn't rare enough in their care.
There is some confusion in the dog names. Aiko and Kimi are both females. Aiko and Kimi have the same dam, Mura, but different sires.
I own Kimi. She has had three litters to date with different sires, and I am in contact with several of the pups owners and am not aware of any issues. My males are Dai, recent import, one litter so far with Kimi; and Shogun (co-owned with Katja and Kris) who is also a recent import and has not yet sired any litters.
Aiko is now retired, there was a forum post some time ago when she was looking for a nice retirement home.
Depending on how old the pups are and when they were whelped, their sire was likely Kuma, Yamato, or Mike. Each of those sires has several wonderful healthy pups to their credit. If the problem was passed from a mix with Aiko, she is no longer being used for breeding.
I highly doubt it's Gangliosidosis, considering the website said death at 14 months of age. Fate & Hugo are 2.5 years old now. There are also other things in there that don't match Fate's condition, not sure about Hugo.
They are from Kuma x Aiko.
A friend of mine who is a DVM has looked at some videos I took of Fate. [ he is not in state ] he's dead sure it's cerebellar hypoplasia or abiotrophy, particularly, based off a video of Fate eating that he specifically requested.
My personal vet also was guessing one of the above two, in addition to taxoplasmosis, canine wobblers, etc. [ the last few being unlikely ]
Likewise, a third DVM, Wraith & Aggro's breeder, who stayed with us a night about a week ago, also thinks cerebellar hypoplasia / abiotrophy. ~
I am so sorry Osy and Holly. I really feel for you both, I would be heart broken.
@Sangmort (Osy), if it is cerebellar hypoplasia, that is caused by a pathogen infecting the female while she is pregnant. I have a cat that has that and with cats they show the symptoms from birth. My cat has a mild case, but some of the videos on youtube show pretty severe cases. On wikipedia (I know, not maybe 100% accurate), it says that CH develops more slowly in dogs. And with eating, at least in cats, they kind of tremor as they move to and from the dish, having a hard time judging the distance from their mouth to the dish.
But just throwing this out there because it may be that it is not genetic, as CH is thought to be caused by an infection while the female is pregnant. Because Tenshou (Kuma) has had many normal puppies. And Hugo and Fate were in the same litter, correct, so they would have been in utero together (if it was caused by a pathogen, ie, CH)?
Certainly it would be of interest to the shikoku community that we clearly track this kind of issue. And if it will eventually be possible to tell if Hugo and Fate have CH or rather have Cerebellar Abiotrophy (which is genetic). CA seems to occur in many different dog breeds, and if Wikipedia is to be believed, the symptoms show up at different times depending on the dog breed.
This is a horrible thing for you and your dogs to have to deal with. These dogs were sure lucky to end up with people like you guys who are making them as comfortable as possible thru this. So sorry for you both and your pups (
Just read this thread. I had a foster rescued Akita with a condition like this; he had tremors when I got him a 3 months, which got worse with age; he eventually had bad seizures and was euthanized when he was about 2. I have his records and can look this up. He went to live with our puppy school trainer after puppy class, and I saw him infrequently but saw photos and videos of his condition. He had a neuro workup with no specific results, possible CH or CA; some results pointed to a storage disease so samples were sent to Urs Giger at U Penn, the canine storage disease specialist. Those were negative. He had a necropsy and samples were sent to Giger, then, too, but the results were still negative. Nothing unusual was seen on the necropsy and samples were sent to a researcher working on inherited neurological diseases, but I didn't hear anything about those, maybe negative for what he was looking for. I have a feeling I just wrote all this; if I did, I'm sorry.
Comments
sIRE: Ch. Tenshou Go Awahakuga (Kuma) or Akashima's Kochi Ken Kaiuri
DAM: Daiyuume Go Iyo Tsukasasou (Sachi) or Ch. Akashima's Kochi-Ken Harayuki (Yuki)
http://www.shiba-dog.de/ShibaDog-en.htm
Can Dr. Yamato who led the study be asked to test cheek cell swab samples from Hugo and Fate? (Easier to ship cheek swabs than blood.)
Can he see if it's the same Shiba gene mutation so that a genetic test can be made to find carriers in Shikoku?
I own Kimi. She has had three litters to date with different sires, and I am in contact with several of the pups owners and am not aware of any issues. My males are Dai, recent import, one litter so far with Kimi; and Shogun (co-owned with Katja and Kris) who is also a recent import and has not yet sired any litters.
Aiko is now retired, there was a forum post some time ago when she was looking for a nice retirement home.
Depending on how old the pups are and when they were whelped, their sire was likely Kuma, Yamato, or Mike. Each of those sires has several wonderful healthy pups to their credit. If the problem was passed from a mix with Aiko, she is no longer being used for breeding.
Katja would know specifics if the owner does not.
-Mac
They are from Kuma x Aiko.
A friend of mine who is a DVM has looked at some videos I took of Fate. [ he is not in state ] he's dead sure it's cerebellar hypoplasia or abiotrophy, particularly, based off a video of Fate eating that he specifically requested.
My personal vet also was guessing one of the above two, in addition to taxoplasmosis, canine wobblers, etc. [ the last few being unlikely ]
Likewise, a third DVM, Wraith & Aggro's breeder, who stayed with us a night about a week ago, also thinks cerebellar hypoplasia / abiotrophy. ~
@Sangmort (Osy), if it is cerebellar hypoplasia, that is caused by a pathogen infecting the female while she is pregnant. I have a cat that has that and with cats they show the symptoms from birth. My cat has a mild case, but some of the videos on youtube show pretty severe cases. On wikipedia (I know, not maybe 100% accurate), it says that CH develops more slowly in dogs. And with eating, at least in cats, they kind of tremor as they move to and from the dish, having a hard time judging the distance from their mouth to the dish.
http://en.wikipedia.org/wiki/Cerebellar_hypoplasia_(non-human)
I am so sorry to hear this for you both.
But just throwing this out there because it may be that it is not genetic, as CH is thought to be caused by an infection while the female is pregnant. Because Tenshou (Kuma) has had many normal puppies. And Hugo and Fate were in the same litter, correct, so they would have been in utero together (if it was caused by a pathogen, ie, CH)?
Certainly it would be of interest to the shikoku community that we clearly track this kind of issue. And if it will eventually be possible to tell if Hugo and Fate have CH or rather have Cerebellar Abiotrophy (which is genetic). CA seems to occur in many different dog breeds, and if Wikipedia is to be believed, the symptoms show up at different times depending on the dog breed.
http://en.wikipedia.org/wiki/Cerebellar_abiotrophy
So sorry for you both and your pups